Novan Receives Additional Funding to Support Its Nitric Oxide-Based Therapies

Novan has entered into a common stock purchase agreement with Aspire Capital Fund, LLC, a Chicago-based institutional investor. The agreement provides additional financing to fund Novan’s nitric oxide technology platform, which has potential indications in dermatology, women’s health and gastroenterology. The company currently has four nitric oxide-based products with dermatologic indications in the pipeline, including SB204 for acne, SB206 for molloscum, SB208 for tinea pedis, and SB414 for the treatment of atopic dermatitis and psoriasis.

Sebacia Demonstrates 85 Percent Improvement in Acne at 12 Months

Sebacia Real World Results

Sebacia, a privately held, commercial-stage dermatology and aesthetics company, announced new results from its real-world study in Europe evaluating Sebacia Microparticles for treatment of acne. The study demonstrated an average 85 percent improvement in facial acne at 12 months.

Sebacia Microparticles were cleared in 2018 by the U.S. Food and Drug Administration (FDA) for use as an accessory to 1,064nm lasers to facilitate photothermal heating of sebaceous glands for the treatment of mild-to-moderate inflammatory acne vulgaris.

New Acne Topical Now Available in the U. S.

New Tretinoin-based topical

Ortho Dermatologics, the dermatology division of Bausch Health Companies, has announced the U.S. launch of ALTRENO (tretinoin) Lotion, 0.05% for the topical treatment of acne vulgaris in patients 9 years of age and older. In clinical trials, ALTRENO Lotion was shown to be effective and generally well tolerated. The formulation includes known moisturizers hyaluronic acid, glycerin and collagen.

Sebacia Microparticles Promoted as Contrast Enhancing Agents

Histopathology showing microparticles in skin

Sebacia, the developer of Sebacia Microparticles, which are being investigated for use in acne and laser hair removal, presented new data on the feasibility of using the microparticles as an adjunct to existing imaging modalities to measure hair follicles and sweat glands during the 2018 American Society for Laser Medicine and Surgery (ASLMS) conference in April.

RETIN-A MICRO 0.06% Now Available To Physicians

New acne treatment available

Topical acne treatment, RETIN-A MICRO (tretinoin) gel microsphere 0.06% from Ortho Dermatologics, is now available commercially to healthcare professionals. The gel features a microsponge delivery system technology that helps to control the release of tretinoin and improve photostability, plus a pump dispenser for controlled and consistent dosing. Clinical data provided to the U.S. Food and Drug Administration showed 98.7% (252/255) and 94% (210/224) of patients found RETIN-A-MICRO to be tolerable.

MDacne Launches Mobile Acne Analysis App With Customizable Skincare Line

Dermatologist and software engineer launch at-home acne care platform

Dermatologist Yoram Harth, MD, and his son, Oded Harth, a software engineer, have launched MDacne, a mobile acne analysis app that ties into a customized acne treatment product line.

Users who download the app can take a picture of themselves on their mobile devices. The platform then uses proprietary computer vision technology to assess the user’s skin and recommends a customized kit of anti-acne topicals. MDacne subscribers can chat with a dermatologist through the app, track their skin's improvement, and read free tips on how to reduce breakouts.