Photodynamic therapy

A Light Boost

Offering photodynamic therapy for skin rejuvenation.
A Light Boost

Photodynamic therapy (PDT), the practice of irradiating a photosensitizing agent to damage cells, has a broad—and growing—range of indications. In dermatology, PDT is used to target precancerous and cancerous lesions, reduce the redness of rosacea, and destroy P. acnes bacteria and the sebaceous glands to clear acneic skin. In aesthetic medicine, PDT is also being used as a skin rejuvenation treatment.

ALA PDT Effective for Acne in Asian Skin

ALA PDT Effective for Acne in Asian Skin

In a study published in the Journal of Drugs in Dermatology (June 2016), researchers Yik Weng Yew, MD, MPH, et al, investigated whether photodynamic therapy (PDT) using topical application of aminolevulinic acid (ALA) is an effective treatment regimen for acne vulgaris in Asian skin. They found that a single treatment session of 5%-ALA PDT reduced truncal acne lesions by more than 60% in their Asian patients.

Acne-Inhibiting PDT Protocol

ALA-PDT with high-fluence red light has shown impressive results in reducing acne lesions. Unfortunately, the pain and swelling associated with the treatment make it a poor choice for acne patients, particularly those with facial acne. In an effort to maintain results but reduce pain, Fernanda Sakamoto, MD, and her colleagues performed a randomized, double-blinded control study to compare conventional ALA-PDT to a new inhibitory PDT method (iPDT) that involves irradiating the aminolevulinic acid (ALA) with low-levels of blue light during the incubation period.