undereye bags

Unpacking Undereye Bags

Topokine begins late-stage trials of XAF5 for topical reduction of steatoblepharon.
Unpacking Undereye Bags

It was an accident, really. Michael Singer, MD, ophthalmologist and instructor of pharmacology at Harvard University, and Murat Kalayoglu, MD, ophthalmologist and researcher with expertise in lipid metabolism, were investigating XAF5, an experimental prostaglandin ointment originally developed at Harvard University for the treatment of glaucoma. As patients used the eye drops meant to decrease eye pressure, they and their doctors began to notice prostaglandin-associated periorbitopathy (PAP), a side effect that had been documented with other prostaglandin treatments.