Newsmakers

Newsmakers: Transcription Factor Ybx1

Researchers have identified the transcription factor that may hold the key to reversing age-related cellular changes.
Calorie Restricted Diets and Aging

Several studies have shown that calorie-restricted diets increase life span. But how? In an effort to understand the mechanisms by which caloric restriction prolongs life, a team of researchers from the United States and China built single-cell and single-nucleus transcriptomic atlases across various tissues of aging rats.

Newsmakers: HairMetrix

Canfield is introducing an innovative, AI-driven hair analysis and consultation system for aesthetic practitioners.
Canfield Hair Analysis System

Hair loss and thinning hair affect the majority of men and women as they age. In the past few years, demand for hair restoration procedures has grown as new, more effective treatments come to market. To help practitioners and patients track progress, Canfield Scientific—maker of the Visia Skin Analysis system—has developed HairMetrix, an artificial intelligence (AI)-driven, noninvasive consultation tool.

Newsmakers: Mark Constantian, MD

Dr. Mark Constantian's new book chronicles the link between childhood trauma, shame and plastic surgery addiction.
Childhood trauma and plastic surgery

"In the early 1990s I saw three rhinoplasty patients within a few months who all had exemplary results, and they all were distraught afterwards,” says plastic surgeon Mark B. Constantian, MD. “One man tried to cut his nose off with a razor and ended up in the emergency room. One woman became a recluse in her home. Another woman gave up her job as a university professor. After surgery they either hated themselves or me, yet they were all positive that if I would only operate again, they would be OK.”

A Sebum-Targeting Laser

A 1,726nm laser prototype presents a potential energy-based cure for acne.
1,927nm laser for acne

For close to a decade, R. Rox Anderson, MD, PhD, and Fernanda Sakamoto, MD, of the Wellman Center for Photomedicine in Boston have been working to develop a laser that can permanently destroy sebaceous glands, offering a potential cure for acne. “If you look at the sebaceous glands, you don't see any pigment in them, yet there are wavelengths in the infrared range where the lipids—the wax esters that are in the gland, in particular—have stronger absorption than the surrounding tissue,” Dr. Anderson explained to MedEsthetics back in 2010.

Triggering Immunity

Nano-pulse electrical stimulation is emerging as a potential treatment for both benign and malignant skin concerns.
Pulse Biosciences

Pulse Biosciences, a company that has developed a Nano-Pulse Stimulation (NPS) technology based on the work of researchers at Old Dominion University in Charleston, South Carolina, and the University of Southern California’s Alfred E. Mann Institute for Biomedical Engineering in Los Angeles, is piquing the interest of dermatologists and immunologists.

Newsmakers: Skin of Color Society

A desire to better serve patients of all skin types is fueling impressive growth at the Skin of Color Society.
MedEsthetics May/June 2018 Newsmakers

Skin typing is an important concern for aesthetic practitioners. For years, questions lingered regarding the use of injectables in patients at risk of keloid scarring, and it was only through independent research that these fears were largely laid to rest. Providers also need to look carefully at their settings when treating individuals with darker skin types with laser or energy-based devices due to an increased risk of burning and postprocedure pigmentation problems.

No Pain, Swift Gains

A new neurotoxin with a fast onset of action and shorter duration of effect is in development for aesthetics and pain relief.
Botulinum toxin with faster onset of action on horizon

While the aesthetics industry has been focused on new botulinum toxin products and dosing strategies geared toward increasing longevity of results, a new company Bonti has been developing EB-001, a serotype E botulinum toxin that moves in the opposite direction. “This molecule is very similar to the existing botulinum toxin serotype A products in terms of mechanism of action, however, it has two differentiating factors.

Newsmakers: Hydrating Fillers

Microdroplet injections of low-viscosity hyaluronic acid-based fillers are gaining fans around the globe.
The use of dermal fillers for hydration is making its way to the U.S.

Hydrating fillers—low-viscosity hyaluronic acid-based materials injected superficially throughout the face to improve skin tone—have become popular offerings outside of the U.S. and are finding their way onto aesthetic message boards and review sites, generating significant interest among U.S.-based consumers.

Outside the states, physicians have access to specifically formulated products, such as Juvéderm Hydrate, Restylane Vital and Restylane Vital Light, as well as robust marketing campaigns to educate consumers on these new hydrating treatments.

Photothermolysis With Silver Particles

Two small-scale studies highlight the potential of silver particles to improve the efficacy of laser hair removal and light-based acne treatments.
MedEsthetics July/August 2017 Newsmakers

As aesthetic treatments become more varied and efficacious, there remain some key gaps in treatment options. For example, laser hair removal is one of the most pop­ular services offered in aesthetic practices and medspas, yet permanent hair reduction is not an option for those with blonde and red hair. Dermatologists have long sought an alternative to systemic treatments for those with moderate-to-severe acne, and while laser treatments have shown promise, their efficacy is short-lived and inconsistent.