PRF May Extend Longevity of Fat Grafts

PRP v. PRF for Fat Graft Longevity

A "second-generation" platelet concentrate called platelet-rich fibrin (PRF) might enhance the outcomes of fat grafting for plastic surgery procedures, according to the results an experimental study in the June issue of Plastic and Reconstructive Surgery. The rabbit study from Shaoheng Xiong, MD, and colleagues of Fourth Military Medical University in Xi'an, Shaanxi, China, compared fat enriched with PRF to fat enriched with platelet-rich plasma (PRP).

Chemical Peels More Effective Than PRP for Periorbital Hyperpigmentation

Chemical Peels More Effective Than PRP

A randomized study, published in the Journal of Cosmetic Dermatology (online April 25, 2019) found that chemicals peels are significantly more effective at reducing periorbital hyperpigmenation than injection of platelet-rich plasma. Researchers Noha Kamel, MD, et al, treated 42 patients, who were randomly assigned to one of two groups. Group A received four sessions of chemical peeling using trichloroacetic acid and lactic acid, while group B underwent four sessions of PRP injection at two week intervals.

Targeted Delivery

The most promising aesthetic indications for laser- and microneedling-assisted topical delivery.
MedEsthetics March 2019

Laser-assisted drug delivery is being used in multiple specialties to improve outcomes and enhance the efficacy of topical medications. In aesthetics, practitioners are delivering topicals, such as platelet-rich plasma, active skincare ingredients and prescriptions, including minoxidil and bleaching agents, through the microchannels created by fractional ablative laser and microneedling.

PRP For Facial Rejuvenation

PRP for facial rejuvenation

A recent study published in JAMA Dermatology (November 7, 2018) found that platelet-rich plasma (PRP) injections are effective in improving the texture of aging skin.

Murad Alam, MD, et al, performed a randomized clinical trial of 27 subjects (ages 18 to 70) with bilateral cheek rhytids of Glogau class II or greater. Each received 3mL intradermal injections of PRP to one cheek and sterile normal saline to the contralateral cheek. They participants did not know which side was injected with saline vs. PRP.

PRP Effective for Female Pattern Hair Loss

PRP Improves Hair Loss In Women

A randomized, placebo-controlled study from the University of Cairo in Egypt found that platelet-rich plasma (PRP) injections improved hair density and thickness in women with female pattern baldness. Abeer Attia Tawfik, MD, PhD, and Mai Abdel Raouf Osman, MD, PhD, enrolled 30 female patients diagnosed with female pattern hair loss (ages ranged from 20 to 45 years), who had not received topical or systemic treatments for hair loss in the previous three months.