Sebacia Microparticles Promoted as Contrast Enhancing Agents

Histopathology showing microparticles in skin

Sebacia, the developer of Sebacia Microparticles, which are being investigated for use in acne and laser hair removal, presented new data on the feasibility of using the microparticles as an adjunct to existing imaging modalities to measure hair follicles and sweat glands during the 2018 American Society for Laser Medicine and Surgery (ASLMS) conference in April.

Researchers Merete Haedersdal, MD, PhD, clinical professor of dermatology at the University of Copenhagen, Denmark and director of Laser Dermatology Clinic at Bispebjerg University Hospital, and her team used reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) to visualize distribution of the microparticles and evaluate their potential use as a contrast enhancing agent.

“Using accessible bedside imaging tools, we were able to determine that the gold microparticles localized to hair follicles and eccrine ducts and were not visible in the surrounding skin,” said Dr. Haedersdal. “The specific localization and hyperreflectivity of the gold could allow us to improve the diagnostic accuracy in some skin diseases.”

“As we continue to develop our proprietary microparticle treatment for mild-to-moderate acne, this study highlights the applicability of Sebacia Microparticles as a tool that could also be utilized for diagnostics,” said Anthony V. Lando, CEO of Sebacia. “Similar to our acne therapeutic, which is specifically designed to work with dermatologist-owned hair removal or pigmented lesion treatment laser systems, this study is another example of how our gold microparticles could be used in combination with tools, like RCM and OCT, which are readily available to many physicians.”

Image courtesy of Sebacia