Commensal Microbes Trigger Repair in Injured Skin

Research published in Nature Immunology reveals how commensal skin microbes initiate repair responses in injured skin.

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Researchers have uncovered a key role of commensal skin microbiota in the wound healing process, according to a new study published in Nature Immunology.

Here, scientists show that commensal bacteria colonizing skin wounds trigger the activation of neutrophils. This initiates a cascade (detailed in the article abstract) that ultimately produces type I interferon (IFN).

IFN accelerates wound closure by triggering skin inflammation and early, T cell-independent wound repair responses. These produce major growth factors required for healing.

For more information, see the article abstract.

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