Could Targeting This Enzyme Slow Aging? Scientists Reveal PDI's Role in DNA Repair, Longevity

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A recent study published in Aging Cell reveals that an enzyme long known for folding other proteins may also help cells repair DNA damage — a key driver of aging. The enzyme, protein disulfide isomerase (PDI), has been shown to step into an unexpected role: repairing double-strand DNA breaks through a redox-dependent mechanism, ZME Science explained. In doing so, it may offer a new lever for slowing the aging process itself.

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