SVF Gel Offers Long Term Improvement for Infraorbital Hollows

Injection of a stromal vascular fraction gel increased volume in infraorbital hollows with excellent retention rates.

Stromal vascular fraction gel for infraorbital hollows
Stromal vascular fraction gel for infraorbital hollows

Stromal vascular fraction gel (SVF-gel) is an effective filler for tear trough deformity combined with infraorbital hollows, according to the results of a study by Sai Luo, MD, PhD, et al, published in Dermatologic Surgery (December 2020).

From July 2017 to June 2018, 33 patients underwent autologous fat aspiration. Patients with bilateral Barton I/II; tear trough deformity and infraorbital hollows were treated with SVF gel injection. The investigators evaluated improvement by measuring skin-periosteal depth, 3D volume, global aesthetic improvement scale (GAIS) and patient self-assessment.

Following treatment, skin-periosteal depth improved significantly. The volumetric increment of the tear trough and infraorbital regions increased 2.132 ± 0.671 mL, and the retention rate was 72.87 ± 10.23%. The GAIS showed a high score of 2.5 ± 0.5 points. Patient self-assessment showed satisfactory results for all seven questions on the questionnaire.

The authors concluded, “The high retention rate of SVF-gel suggests that it can provide an effective solution to tear trough deformity accompanied by infraorbital hollows.”


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