A study published in Lasers in Surgery and Medicine (March 2022) found that the Cutera Enlighten 1,064-nm picosecond laser with micrlens array (MLA) was an effective treatment for pore tightening delivering an average of 30% reduction in pore size.
The prospective, single-arm, nonrandomized study included 25 patients with enlarged pores on the nose and both sides of the cheeks (aged 25 to 40 years) who were treated with the laser at four-week intervals. Of these patients 6 (26%) were males and 19 (74%) were females, all with Fitzpatrick skin types III (76%) and IV (24%).
To evaluate the treatment, assessed pore volume using a skin imaging device (Antera 3D CS; Miravex LImited), and two blinded dermatologists rated photographic documentation using identical camera settings, lighting and patient positioning using a Canon PowerShot G9 stand-off camera (OMNIA Imaging System; Canfield Scientific). These assessments were performed at baseline and at 1-, 3- and 6-month follow-ups. Adverse effects were also recorded during each visit.
After three treatments, researchers saw significant reduction of pore size from baseline. The improvement significantly continued from the one month to the six month follow-up visits.
The total average pore size was 1.15652 ± 0.614322 at baseline and 0.8087 ± 0.50515 at six months after the final treatment. There were no cases of dyspigmenation, textural alteration or scarring.