New peer-reviewed research across two of the field’s leading journals, Aesthetic Surgery Journal (ASJ) and Plastic and Reconstructive Surgery (PRS), is signaling a meaningful shift in how regenerative therapies are being used in both clinical and aesthetic settings —one that closely aligns with the work being advanced by Lynch Regenerative Medicine (LRM).
A newly published review in PRS synthesizes more than 30 years of research on recombinant platelet-derived growth factor (PDGF-BB), spanning over 140 clinical studies and 15,000+ patients, reinforcing its safety and efficacy across wound healing, bone regeneration, and soft tissue repair. The paper also highlights growing interest in its use in aesthetic medicine, including skin rejuvenation and post-procedural recovery.
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At the same time, a randomized, controlled clinical trial published in ASJ demonstrates that topical PDGF can significantly improve aesthetic outcomes and patient satisfaction following RF microneedling, outperforming standard post-procedure care across multiple endpoints.
For aesthetic providers, the two peer-reviewed studies indicate a broader industry shift toward growth factors like PDGF emerging as evidence-based tools in aesthetic practice. With increasing scrutiny around growth factors, exosomes and other regenerative treatments, data published in leading journals like Aesthetic Surgery Journal and Plastic and Reconstructive Surgery helps practitioners separate evidence-based solutions from emerging trends.
Together, these publications point to a broader industry shift: growth factors like PDGF — long established in medical and surgical settings — are now emerging as evidence-based tools in aesthetic practice. LRM has been at the forefront of translating this science into real-world applications, most notably through the introduction of ariessence pure PDGF+, a topical formulation combining recombinant PDGF with hyaluronic acid designed to enhance recovery and optimize results.
With increasing scrutiny around regenerative treatments, this level of peer-reviewed validation reinforces PDGF as one of the most clinically substantiated approaches in aesthetics today, and positions LRM as a key player helping bring that science into practice.
