Vytrus Biotech Develops Plant Exosomes, Presents Customizable Exosomic Peptides

Centella asiatica plant exosomes were developed to activate cutaneous genes related to aging, the skin barrier and hydration in keratinocytes, reportedly with 'powerful regenerative and anti-wrinkle effects on the skin.'
Centella asiatica plant exosomes were developed to activate cutaneous genes related to aging, the skin barrier and hydration in keratinocytes, reportedly with "powerful regenerative and anti-wrinkle effects on the skin."
Image by Kanchanit at Adobe Stock

Vytrus Biotech has leveraged its biotech expertise to develop intact plant exosomes for skin and hair care applications; in relation, it has patented the concept of Exosomic Peptides. As the company explains, exosomes (aka ectosomes) are small extracellular vesicles (sEVs) bound by a lipid membrane that hold and protect key "natural biological communicators" for skin care and health benefits — i.e., DNA, RNA, lipids, proteins, cytokines, heat shock proteins, enzymes, antioxidants and other bioactives. These entities, including an array of plant peptides (which the company refers to as Exosomic Peptides), can be manipulated for desired skin and hair benefits.

See related: Vytrus Biotech Highlights Sun-Microbiota-Skin Axis, Launches Photobiome

Plant Exosomes for Custom 'Cross-kingdom' Communication

As the company explains, contrary to synthetic and biomimetic exosomes currently available, Vytrus' exosomes are created from actual plants in culture using biotechnology. These exosomes are fully intact and structurally similar to mammalian exosomes that, per the company, "can penetrate and deliver molecular information to human cells very effectively, allowing cross-kingdom communication in cosmetics."

The company's plant cell cultures reportedly show a high exosome concentration vs traditional plant sources (i.e., billions of exosomes/mL). In addition, it is possible to customize and guide the plant cells to produce different kinds of exosomes for skin and hair care.

For example, Vytrus Biotech developed Curcuma longa exosomes to improve skin hydration and regeneration, hair density and hair loss. Also, Centella asiatica exosomes to activate cutaneous genes related to aging, the skin barrier and hydration in keratinocytes (increased expression of type I collagen, inhibition of elastase, etc.), with "powerful regenerative and anti-wrinkle effects on the skin."

In addition, as noted, the company delved into the depths of natural plant exosomes and identified "an astonishing diversity of plant peptides," coined by Vytrus as Exosomic Peptides. Per the company, its exosome products offer a cocktail of these natural plant peptides for anti-aging, anti-inflammatory and anti-wrinkle activities, among others.

See archived: Vytrus Biotech Debuts Elaya Renova for Hair/Scalp 'Tensegrity,' New Brand Identity

Harboring Cosmetic Benefits

According to Vytrus Biotech, plant exosomes can serve multiple cosmetic functions, including:

  • anti-inflammation,
  • well-aging,
  • immunomodulatory,
  • healing,
  • hydration,
  • extracellular matrix protein synthesis,
  • protection,
  • microbiota modulation,
  • skin regeneration; and
  • balancing skin homeostasis, among others.

Thus, the exosomes are positioned as functional, sustainably derived ingredients that align with consumer demand for effective natural skin and hair care. 

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