Six treatment sessions with a fractional radiofrequency (RF) device with novel 1-mm long ultra-thin electrode pins (Lumenis Legend Pro) improved skin laxity and wrinkles, according to both blinded evaluators and subjects. For “Clinical and histologic evaluation of a fractional radiofrequency treatment of wrinkles and skin texture with novel 1-mm long ultra-thin electrode pins,” (Lasers in Surgery and Medicine, July 20, 2021), Arielle N. B. Kauvar, MD, Amikam Gershonowitz, DVM, treated nine patients (mean age: 47.6, Fitzpatrick skin type II–IV, Fitzpatrick Elastosis Wrinkle Scale [FEWS] score: 3–6).
All subjects underwent six treatment sessions with a fractional RF technology utilizing an array of 6 × 6 1-mm long ultrathin electrodes. Treatment effectiveness was assessed by FEWS and the Global Aesthetic Improvement Scale (GAIS). The investigators also evaluated safety and tolerance.
Three months after that last treatment session, blinded, investigator-assessed FEWS decreased from baseline 4.33 ± 0.67–3.33 ± 0.67; 88.9% of participants showed overall skin improvement using the physician-assessed GAIS; and all subjects reported improvement in skin texture and wrinkles.
The treatment was well tolerated, with no adverse events and no downtime. Histological analysis in a porcine model showed a fractional pattern of epidermal ablation and dermal coagulation with intervening zones of normal healthy tissue. These changes were followed by progressive epithelialization over a period of 13 days.