Skin Care

Recognizing Complications

Injection-related complications occur among even the most well-trained providers; recognizing the warning signs is key to preventing long-term damage.
Recognizing Complications

The 2015 International Society of Aesthetic Plastic Surgery (ISAPS) Global Procedural Survey revealed that botulinum toxin injections and hyaluronic acid (HA) dermal fillers are the two most popular nonsurgical procedures, with about 4.6 million toxin and 2.8 million filler treatments performed worldwide. The survey results also showed that HA filler popularity is on the rise, as that number represents a 6.5% increase over the previous year.

Rosacea and Systemic Disease

New links between rosacea and systemic illnesses highlight the importance of medical histories and underscore the need for healthy skepticism.
Rosacea and Systemic Disease

In recent years, researchers have hypothesized that patients with rosacea may be at higher risk for systemic vascular concerns, such as coronary artery disease, as well as neurological disorders, including depression and anxiety. Most recently, a study in JAMA Neurology (May 2016), questioned whether the increased activity of matrix metalloproteinase (MMP) seen in patients with rosacea may offer a clue for the treatment of Parkinson’s Disease, setting up a tenuous connection between the two illnesses.

Opening Channels

Microneedling is experiencing a huge resurgence as a more affordable alternative to laser resurfacing.
Opening Channels

“The Next Big Thing.” “2016’s Trending Skincare Treatment.” “Our New Favorite Skincare Procedure.” Even if you didn’t see these headlines, you have likely experienced an increase in patients asking about microneedling. Although the procedure has been around for decades, it has recently become a media darling.

Lovely Lips

The key to natural-looking lip augmentation lies in understanding facial anatomy and patient expectations.
Lovely Lips

Lip augmentation is one of the few aesthetic concerns that bridges all age groups. Young patients often come to practices seeking larger, more lustrous lips; while aging patients are dismayed at loss of definition and the appearance of perioral lines and wrinkles. In order to create the aesthetic outcomes these patients seek, one must gain an understanding of their desired outcomes and step back to examine the entire lower face.

Subdermal Depo PRP

A new PRP injection technique may improve outcomes for patients with androgenic alopecia.
Subdermal Depo PRP

Androgenic alopecia (AA) is one of the most prevalent aesthetic concerns, affecting an estimated 30% of men over the age of 40. Building on the potential promise of platelet-rich plasma (PRP) to reduce hair loss, I have developed a new technique that involves injecting a bolus of PRP into the subcutis to reverse the effects of AA. The technique—which I refer to as Rapaport Subdermal Depo PRP Injection—has become one of my favorite and most gratifying cosmetic procedures, as I see immediate changes in my patients’ emotional states once their hair is improved.

A Light Boost

Offering photodynamic therapy for skin rejuvenation.
A Light Boost

Photodynamic therapy (PDT), the practice of irradiating a photosensitizing agent to damage cells, has a broad—and growing—range of indications. In dermatology, PDT is used to target precancerous and cancerous lesions, reduce the redness of rosacea, and destroy P. acnes bacteria and the sebaceous glands to clear acneic skin. In aesthetic medicine, PDT is also being used as a skin rejuvenation treatment.

Pierre Fabre Partners With Piqur

Swiss pharmaceutical company Piqur Therapeutics and French pharmaceutical group Pierre Fabre have signed a collaboration agreement for the development of Piqur’s lead compound PQR309, a PI3K/mTOR inhibitor, in dermato-oncology. Piqur and Pierre Fabre’s R&D teams will work together on the evaluation and development of dermatological formulations of PQR309 across multiple therapeutic indications.

Determining Microneedling Depth

Determining Microneedling Depth

Practitioners should be aware that electric microneedling device length settings do not always correspond to actual depth of penetration. For “Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns” (Aesthetic Surgery Journal, January 2017), Gordon H. Sasaki, MD, used excised, microneedled pre-auricular skin to determine actual depths of tissue penetration with six needle lengths.

Revance Therapeutics Begins RT002 Studies

Revance Therapeutics commenced a pair of double-blind, placebo-controlled, North American Phase 3 trials to evaluate single injections of drug candidate DaxibotulinumtoxinA (RT002) for the treatment of glabellar lines in about 600 total patients. The trials follow the successful BELMONT study that showed RT002 delivered six-month duration of effect, with no ptosis at the 40-unit level, in treating frown lines.

Maximizing Safety During Facial Fillers

Maximizing Safety During Facial Fillers

In an article published in Plastic and Reconstructive Surgery (January 2017), Jack F. Scheuer III, MD, et al, outline general principles and safe practices for ensuring increased safety and better outcomes when administering facial filler injections. They posit that practitioners can tailor injection techniques to prevent vessel injury and avoid cannulation by considering the depth and the location of the vasculature within six “facial danger zones,” i.e., brows/glabella, temporal region, infraorbital area, lips/commissure, nasolabial folds and nose.