XERF System with Needle-Free RF Technology Now Available in the U.S. Following FDA Clearance

Woman with closed eyes touching her face in peaceful skincare moment
The XERF system combines 6.78 MHz and 2 MHz RF energy to target multiple skin depths, including heating fibrous septa.
Courtesy of Prostock-studio at Adobe Stock

Energy-based device company, Cynosure Lutronic, received clearance for its XERF system, a radiofrequency technology for face and neck skin tightening, in August 2025. The XERF system provides multi-frequency monopolar RF treatment and is starting to see itself rolled out in U.S. practices. 

Predominantly manufacturing lasers and RF devices, this device was created by Cynosure Lutronic to tighten skin without the need for numbing, needles or downtime, meant for all skin types, per an Aug. 18 press release. Since this is a monopolar RF treatment, the device combines 6.78 MHz and 2 MHz frequencies, enabling providers to deliver energy at multiple tissue depths, including to heat the fibrous septa for reportedly lasting tightening effects. 

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